Tubulology (Regulation of Polarity Signaling during Morphogenesis, Remodeling, and Breakdown of Epithelial Tubule Structure)

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2014-2015: Proposed research project 03

Molecular mechanisms by which stiffness of extracellular matrix regulates the formation of epithelial tubular structure

Leader :

Noriyuki Kioka

Tomiyama, L., Sezaki, T., Matsuo, M., Ueda, K., Kioka, N. Loss of Dlg5 expression promotes the migration and invasion of prostate cancer cells via Girdin phosphorylation. Oncogene 34: 1141-1149, 2015.
Yamashita, H., Ichikawa, T., Matsuyama, D., Kimura, Y., Ueda, K., Craig, S.W., Harada, I., Kioka, N. The role of the interaction of the vinculin proline-rich linker region with vinexin alpha in sensing the stiffness of the extracellular matrix. J. Cell Sci. 127: 1875-1886, 2014.